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Juvederm vs. Restylane: Who Is the Winner in This Battle?

12 Jan 2022
Juvederm vs. Restylane: Who Is the Winner in This Battle?

In the 21st century, a dermal filler injection has transformed from a luxurious procedure for celebrities into an affordable cosmetic treatment for average people. For instance, about 3 million dermal filler injections were performed in the U.S. last year.

Moreover, there exists a wide range of dermal filler brands these days, such as Juvederm, Restylane, Belotero, Radiesse, Teosyal, and many others. While each product has its own peculiarities, it might be difficult to decide which one will fit your needs best.

In the information below, we will compare and contrast two well-known and beloved dermal fillers, namely Juvederm and Restylane. So, let’s figure out what product will be the winner in this battle right away!

A Few Words on Dermal Filler Treatments

A dermal filler treatment is a cosmetic procedure that involves an injection of a special gel-like preparation into a patient’s skin tissue for a number of aesthetic indications, such as:

  • Lip augmentation and hydration;
  • Fine lines, wrinkles, and folds smoothing;
  • Chin and cheek augmentation;
  • Face contouring;
  • Pigmentation reduction;
  • Etc.

Depending on their main active ingredient, there exist the following dermal filler types:

  • Hyaluronic acid-based;
  • Calcium hydroxyapatite-based;
  • Poly-L-lactic acid-based;
  • Polymethylmethacrylate-based;
  • Etc.

While such component as hyaluronic acid or calcium hydroxyapatite is naturally occurring substance, poly-L lactic acid and polymethylmethacrylate are created in an artificial way. Moreover, some types of dermal fillers might also include a local anesthetic (such as lidocaine) in their composition. You can order any of these types of dermal fillers on Dkderma.

Among the most well-known brands of dermal fillers are:

  • Juvederm;
  • Restylane;
  • Radiesse;
  • Belotero;
  • Saypha;
  • And many more.

When it comes to their composition, treatment areas, procedure protocol, and result, each above-mentioned brand has its own peculiarities. So, let’s briefly touch upon the main characteristics of Juvederm and Restylane.

Juvederm Injections Peculiarities


Juvederm is a brand that is produced by the French-Canadian manufacturer Allergan. Its product line consists of a number of preparations such as:

All Juvederm dermal fillers are based on cross-linked hyaluronic acid of non-animal origin which is manufactured by means of either Vycross or 3D-Matrix technology. As well, they might either include or do not include lidocaine in its composition.

In most cases, Juvederm is applied to treat the facial tissue. When being more precise, it is usually administered into:

  • Cheeks;
  • Perioral area (wrinkles and lines around the mouth);
  • Area around the eyes;
  • Lips.

While providing a patient with immediate results after the procedure, Juvederm products ensure a long-lasting effect for up to 24 months. Buy Juvederm in US at Dkderma.

As a side note: The Juvederm brand is approved by FDA since 2006.

Restylane Injections Peculiarities


Restylane, in its turn, is a brand that is manufactured by Q-Med, which is a division of the Swiss pharmaceutical company Galderma. Restylane’s product range includes a wide range of preparations, namely:

The above-mentioned products have cross-linked hyaluronic acid of non-animal origin which is manufactured with the help of one of the brand’s patented technologies: NASHA and OBT (Optimal Balance Technology). Similar to Juvederm products, Restylane ones might come with or without lidocaine. At Dkderma you can buy Restylane online and save up to 40%.

Restylane products are usually used to treat facial wrinkles and lines. Namely, they are especially effective to rejuvenate and enhance:

  • Nasolabial folds;
  • Smile lines (or, as they are also called, “marionette lines”);
  • Lips.

Apart from these facial areas, Restylane products might also be used to treat hands.

The result you achieve after the injection of Restylane will last up to 24 months in most cases.

As a side note: Restylane products are FDA-approved.

Juvederm vs. Restylane Skin Injection Procedures: A Comparison

After having a short overview of Juvederm and Restylane injectable dermal fillers, let us compare and contrast both brands in order to figure out which one is better.


The composition of Juvederm and Restylane products is pretty similar. They both contain cross-linked hyaluronic acid of non-animal origin as their principal active ingredient. Furthermore, both brands manufacture products with and without lidocaine.

However, each brand has its own manufacturing technologies. Namely, Juvederm’s Vycross and 3D-Matrix stands side-by-side with Restylane’s NASHA and OBT. It’s difficult to state what technology is the best, as all of them are well-developed and efficient.

As a side note: Since both Juvederm and Restylane are based on hyaluronic acid, they are pretty safe and rarely lead to severe allergic reactions or side effects.


The texture is the main peculiarity that makes Juvederm different from Restylane, namely:

  • On the one hand, Juvederm has an extremely smooth consistency;
  • On the other hand, Restylane is a little bit more granular.

As a result, the smoothness of Juvederm allows it to effectively fill in moderate to severe facial wrinkles. While the granularity of Restylane makes it an efficient volumizer and shaper that will firmly stay in the intended place after being injected.

Thus, neither the smooth nor granular texture of a dermal filler is better or worse, as they both have different indications.

Treatment Areas

Health care practitioners use Juvederm and Restylane dermal fillers to rejuvenate and enhance the skin of the face in most cases. However, both brands specifically target slightly different facial areas. For instance:

  • Juvederm is often administered to the perioral area, area around the eyes, and cheeks;
  • Restylane, in its turn, is injected into the mid-face and the nasolabial area (the one around the nose and mouth) in most cases.

As a side note: Despite the fact that different formulas of Juvederm and Restylane are frequently used to reduce age-related signs in various facial areas, they can substitute one another in most cases. As well, please note that each brand has a variety of preparations with concrete indications in its product line.

As well, the two brands are efficient when it comes to treating lips. Namely, Juvederm and Restylane are oftentimes used to both smooth lip lines and volumize lips.

Unlike Juvederm, Restylane is also oftentimes used as the skin aging treatment for hands.


Juvederm and Restylane’s administration procedures are almost identical. They both:

  • Involve a certified health care practitioner who will inject the preparation in the proper dermal layer with the help of a needle;
  • Last about 30 minutes (however, everything depends on the treatment area and individual condition of a patient);
  • Require little to no downtime;
  • Are almost pain-free;
  • Do not lead to any severe side effects or complications. Naturally, you might experience such symptoms as skin irritation or redness after the treatment, but they tend to disappear within a short time period and do not require any medical supervision in most cases.

As a side note: In order to minimize the possibility of unwanted complications such as permanent scarring or blood vessel destruction, rely on knowledgeable health care practitioners. As well, make sure to let them know whether you are predisposed to the increased risk of excessive scarring, bleeding disorder, or any other health complications (like, for example, pigmentation disorders).

When it comes to the number of procedures you have to undergo to achieve the desired result, little depends on the brand. No matter whether you use Juvederm or Restylane, it is your individual skin condition, age, lifestyle, and health that define how many injections you will need.


Both Juvederm and Restylane offer amazing natural-looking results. These dermal fillers smooth lines, reduce wrinkles, and plump lips in an efficient way. However, while Juvederm provides a patient with an immediate effect, it might take a day till the result of Restylane become visible.

When it comes to the duration of Juvederm and Restylane results, everything depends on the individual peculiarities of each and every patient. On average, both products might provide you with a long-lasting effect of up to 24 months.

A Bottom Line

All in all, there is no clear frontrunner in Juvederm vs. Restylane comparison. While each brand has its own peculiarities, it is the task of your health care practitioner to define which option will be the most beneficial in your individual case.

However, one thing remains clear: both Juvederm and Restylane are worthy treatment options that can profoundly rejuvenate your skin and enhance your overall beauty!

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